Domperidone: How it works and how it compares to Reglan
Several medications have, as a side effect, the production of breastmilk. Digitalis, cholopramzine and other major tranquilizers are just a few of them. With medical management, it is not necessary to have been pregnant in order to produce breastmilk.
Domperidone is an anti-emetic or anti-nausea drug that was initially prescribed for people with upper gastrointestinal problems. Domperidone is not a hormone but it has a side effect that results in an increase in prolactin levels. It was discovered that, when some women would take the drug, this increase in prolactin levels could in turn cause lactation.
As with most drugs, very little of the domperidone ends up in the breastmilk. The baby gets only minute amounts. There is another similar drug that is found in the US called Reglan (Metoclopramide). However, it is not recommended for long-term use in lactating women. It crosses the blood-brain barrier and can cause neurological problems and depression. Note that, according to the the American Academy of Pediatrics classification, Reglan (metoclopramide) is a drug “whose effect on nursing infants is unknown or may be of concern.”
Domperidone is not known to cross the blood-brain barrier in significant amounts and is used to treat chronic conditions that require its long-term use. It is not known to cause depression. Since domperidone does not cross the blood-brain barrier it is much safer for mother and baby. They even give domperidone to babies in Canada suffering from from severe regurgitation. Right now domperidone is not widely available in the US except at a few compounding pharmacies, but domperidone has been approved for use in breastfeeding mothers by the American Academy of Pediatrics.
Newman-Goldfarb Protocols for Induced Lactation® © 2002-2019
Jack Newman, MD, FRCPC and Lenore Goldfarb, PhD, CCC, IBCLC, ALC
If you value this service, kindly consider a donation to the Canadian Breastfeeding Foundation (registered charity). Earmark the donation for the International Breastfeeding Centre (Newman Breastfeeding Clinic) and/or the Goldfarb Breastfeeding Program.
Donate online: canadahelps.orgDonate by mail: Canadian Breastfeeding Foundation, 5890 Monkland Ave, Suite 16, Montreal, Quebec, Canada H4A 1G2.
© 2002-2019 Lenore Goldfarb, PhD, CCC, IBCLC, ALC and contributing authors to AskLenore.info. All rights reserved.
Disclaimer: The information provided on this website is for general informational purposes only and does not constitute medical advice. You should not rely on this information as a substitute for, nor does it replace, professional medical advice, diagnosis, or treatment. If you have any specific questions or concerns about any health issue, you should consult with a qualified healthcare provider.
The AskLenore administration is not affiliated with, nor sponsored by, nor do we sell or receive any commissions or incentives from, any of the products or services that we link to on this website. Therefore, we are not responsible for the accuracy, quality, availability, or suitability of said products or services. You should always do your own research and due diligence before purchasing or using any product or service that we link to on this website.
The views and opinions expressed on the message boards are those of the authors and do not necessarily reflect the official policy or position of asklenore.info. Any content provided by our users are of their opinion and are not intended to malign any religion, ethnic group, club, organization, company, individual or anyone or anything.