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Nipple pain caused by Candida albicans

By Carole Dobrich RN, IBCLC, from Dr. Jack Newman’s candida protocol (with permission) & Dr. Jay Gordon’s web site

The pain caused by a Candidal infection is generally different from the pain caused by poor positioning and/or ineffective suckling.

The pain caused by a Candidal infection:

Please Note:

  1. The baby does not have to have thrush in his mouth.
  2. A Candidal infection of the nipple may be combined with other causes of soreness.
  3. Treat both mother and baby, even if only one has symptoms.

Step one: start with Gentian Violet

Once a day for 4 to 7 days. If pain is gone after 4 days, stop gentian violet.

If better, but not gone after four days, continue for 7 days. Stop after 7 days no matter what.

If not better at all at 4 days, stop the gentian violet, continue with the ointment as below and call your doctor.

Gentian violet is available without prescription but is not available at all pharmacies, so call your pharmacy to confirm they have it before going out to get it. You may need to call several pharmacies to find one that has it.

Using Gentian Violet:

It is messy, and will stain clothing (it will wash out), but will not stain skin. The baby’s lips will turn purple, but the purple will disappear after a few days.

  1. About 10 ml (two teaspoons) of gentian violet is more than enough for an entire treatment.
  2. Many mothers prefer doing the treatment just before bed so that they can keep their nipples exposed and not worry about staining their clothing. The baby should be undressed to his diaper, and the mother should be uncovered from the waist up. Gentian violet is messy.
  3. Dip a clean ear swab (Q-tip) into the gentian violet.
  4. Put the purple end of the ear swab into the baby’s mouth and let him suck on the swab for a few seconds. The gentian violet usually spreads around the mouth quickly. If it does not, paint the inside of the mouth to cover as much of the inside of the cheeks and tongue as possible.
  5. Put the baby to the breast. In this way, both the baby’s mouth and your nipple are treated.
  6. If, at the end of the feeding, you have a baby with a purple mouth, and two purple nipples, there is nothing more to do. If only one nipple is purple, paint the other one with the ear swab and the gentian violet. In this way, the treatment is finished in one go.
  7. Repeat the treatment each day as described above *.
  8. There is often some relief within hours of the first treatment, and the pain is usually gone or virtually gone by the third day. If it is not, it is unlikely that Candida was the problem, though it seems Candida albicans is starting to show some resistance to gentian violet, as it already has to other antifungal agents. Of course, there may be more than one cause of nipple pain, but after three days the contribution to your pain caused by Candida albicans should be gone. However, if your pain is virtually gone after 3 or 4 days, but not completely, you can use gentian violet a few more days if necessary.
  9. All artificial nipples that the baby uses should be boiled in a large pot with 3 - 4 tblspns of vinegar daily during the treatment, or well covered with gentian violet. Consider stopping artificial nipples.
  10. There is no need to treat just because the baby has thrush in his mouth. The reason to treat is the mother’s and/or the baby’s discomfort. Babies, however, do not commonly seem to be bothered by thrush.
  11. Uncommonly, babies who are treated with gentian violet develop sores in the mouth, which may cause them to reject the breast. If this occurs, or if the baby is irritable while nursing, stop the gentian violet immediately, and contact the clinic. The sores clear up within 24 hours and the baby returns to feeding. If the infection recurs, treatment can be repeated as above. But if the infection recurs a third time, a source of re-infection should be sought out. The source may be the mother who may be a carrier for the yeast (but may have no sign of infection elsewhere), or from artificial nipples the baby puts in his mouth. Treatments of the mother (usually with a medication other than gentian violet) at the same time as treatment is repeated for the nipples will usually eliminate re-infection. Contact the clinic.

Step two: add All purpose nipple ointment (APNO) as below:

The pharmacist mixes it all together and it is applied sparingly after each feeding except the feeding when the mother uses gentian violet. Do not wash or wipe it off, even if the pharmacist asks you to. This ointment can be used for any cause of nipple soreness. Use the ointment until pain free and then decrease frequency over a week or two until stopped.

GSE (2 - 5 drops to 1 - 2 oz water) can be applied to mum’s nipples after nursing and then APNO applied.

Step three: add Grapefruit seed extract

250 mg three times a day orally (taken by the mother), seems to work well in many cases. It can be used instead of fluconazole or in addition to fluconazole in resistant cases.

Grapefruit Seed Extract

Here is the site of the company recommended by Dr Jay Gordon:

It has a lot of information about GSE - here is their dosing info:
Recommended Dosage for NutriBiotic Liquid Concentrate
These recommendations are for NutriBiotic Original GSE. Those using Citricidal Professional Strength liquid concentrate should divide these recommended dosages by three (or multiply by 1/3).

Internal Use Note: Never use full strength, may cause irritation.

Orally. Suggested Use: 5 to 15 drops mixed in 5 ounces of water or juice, 2 to 5 times daily, with or without meals. (Or, take one-two NutriBiotic CapsulesPlus® or one-two NutriBiotic® tablets (125 mg each) 1 to 5 times daily).

Children (under 10 years): 1 to 6 drops mixed in 5 ounces juice, 2 to 3 times daily. Do not use full strength in mouth. Some people think the liquid extract is more effective.

Dr Gordon only uses it topically, as he describes on his website:

Step four:

If pain continues or reoccurs and it is reasonably sure the problem is Candida, add Fluconazole 400 mg (loading dosage), then 100 mg twice daily for at least 2 weeks, until the mother is pain free for a week. The nipple ointment should be continued and the gentian violet can be repeated. If fluconazole is too expensive, ketoconazole 400 mg loading, then 200 mg twice daily for same period of time. If Candida resistant, itraconazole, same dose and time period as fluconazole, though Candida actually is less sensitive to itraconazole, generally, than it is to fluconazole. Fluconazole should not be used as a first line treatment or if nystatin alone does not work (which it usually doesn't).

Step five:

For deep breast pain, ibuprofen 400 mg every four hours may be used until definitive treatment is working (maximum daily dose is 2400 mg/day).

At any time A supplement of high dose acidophilus 1 cap 2 - 3 times daily or BioK 1/2 a pot daily can be added while using the above treatment.

For Baby

Gentian Violet as above and GSE (2 - 5 drops to 1 - 2 oz water) can be used in baby’s mouth prior to nursing. It is best to avoid the possibility of baby associating the bitter taste with nursing. High dose acidophilus powder can be used 1 - 2 times daily on baby’s tongue. Open a capsule or use 1/8 teaspoon of powder, wet finger and dab in powder & let baby suck on your finger. Repeat until all the powder is gone. Baby dose of fluconazole is 6mg/kg loading, then 3mg/kg/day as a single dose.

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